Where is translation occur

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo. Nature , — doi Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44 , — An analysis of 5'-noncoding sequences from vertebrate messenger RNAs. Nucleic Acids Research 15 , — Shine, J.

Determinant of cistron specificity in bacterial ribosomes. Nature , 34—38 doi Restriction Enzymes. Genetic Mutation. Functions and Utility of Alu Jumping Genes. Transposons: The Jumping Genes. DNA Transcription. What is a Gene?

Colinearity and Transcription Units. Copy Number Variation. Copy Number Variation and Genetic Disease. Copy Number Variation and Human Disease. Tandem Repeats and Morphological Variation. Chemical Structure of RNA. Eukaryotic Genome Complexity. RNA Functions. Citation: Clancy, S. Nature Education 1 1 How does the cell convert DNA into working proteins?

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. Aa Aa Aa. Figure Detail. Where Translation Occurs. Figure 3: A DNA transcription unit.

A DNA transcription unit is composed, from its 3' to 5' end, of an RNA-coding region pink rectangle flanked by a promoter region green rectangle and a terminator region black rectangle. Genetics: A Conceptual Approach , 2nd ed. All rights reserved. The Elongation Phase. Figure 6. Termination of Translation. Comparing Eukaryotic and Prokaryotic Translation. References and Recommended Reading Chapeville, F. European Journal of Biochemistry , — Grunberger, D. Nucleic Acids Research 15 , — Pierce, B.

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Flag Content Cancel. Email your Friend. Submit Cancel. This content is currently under construction. Explore This Subject. Applications in Biotechnology. DNA Replication. Jumping Genes. What is RNA synthesis? What is transcription? Why is uracil not used as a nucleotide in DNA?

How does uracil differ from thymine? How does a change in dna affect the protein produced? Question 7fc7e. Impact of this question views around the world. You can reuse this answer Creative Commons License. Translation occurs in a structure called the ribosome, which is a factory for the synthesis of proteins.

The ribosome has a small and a large subunit and is a complex molecule composed of several ribosomal RNA molecules and a number of proteins. Translation of an mRNA molecule by the ribosome occurs in three stages: initiation, elongation, and termination. During initiation, the small ribosomal subunit binds to the start of the mRNA sequence. Next, the large ribosomal subunit binds to form the complete initiation complex.

During the elongation stage, the ribosome continues to translate each codon in turn. Each corresponding amino acid is added to the growing chain and linked via a bond called a peptide bond.